2017 Imaging Research Symposium

The 14th Annual Imaging Research Symposium

Department of Radiology and Biomedical Imaging
University of California, San Francisco

October 10th, 2017

Speaker Presentations:
1:00pm - 4:30pm, Cole Hall, 513 Parnassus Ave.

Posters, Awards and Reception:
4:30pm – 6:00pm, Millberry Union, 500 Parnassus Ave.

Symposium Program
 12:30 pm  Registration & Poster Highlights
Cole Hall
 1:00-1:10 pm  Opening Remarks

Sharmila Majumdar, PhD, Professor and Vice Chair for Research, Department of Radiology and Biomedical Imaging
 1:10-2:50 pm  Oral Presentations (Session I)
Moderators: Janine Lupo, PhD, and Andrew Phelps, MD
 1:10-1:20 pm  StImulus Locked K-space shuffling (SILK) for ultra-high resolution fMRI

An Vu, Alex Beckett, David Feinberg, Pratik Mukherjee
 1:20-1:30 pm  Data-driven Lung Cancer Risk Stratification of Pulmonary Nodules in Chest CT using 3D Convolutional Neural Network

Jae Ho Sohn, Alex Izvorski, Dexter Hadley, Thienkhai Vu
 1:30-1:40 pm  First-in-Human studies with CTT1057, a novel F-18 PSMA PET in prostate cancer

Spencer Behr, Rahul Aggarwal, Youngho Seo, Vahid Ravanfar, Salma Jivan, Jim Slater, James Blecha, Beatrice Langton-Webster, Cliff Berkman, Henry VanBrocklin
 1:30-1:40 pm  Concordance of apparent diffusion coefficient measurements across the NCI Quantitative Imaging Network

David C Newitt, Nola M Hylton, NCI QIN MRI Working Group
 1:50-2:00 pm  Immune-related genetic enrichment in frontotemporal dementia

Iris Broce, Celeste M. Karch, Natalie Wen, Chun C. Fan, Yunpeng Wang, Chin Hong Tan, Naomi Kouri, Owen A. Ross, Günter U. Höglinger, Ulrich Muller, John Hardy, International FTD-Genomics Consortium (IFGC), Parastoo Momeni, Christopher P. Hess, William P. Dillon, Zachary A. Miller, Luke W. Bonham, Gil D. Rabinovici, Howard J. Rosen, Gerard D. Schellenberg, Andre Franke, Tom H. Karlsen, Jan H. Veldink, Raffaele Ferrari, Jennifer S. Yokoyama, Bruce L. Miller, Ole A. Andreassen, Anders M. Dale,, Rahul S. Desikan, and Leo P. Sugrue
 2:00-2:10 pm  A metabolic study of hypoxic ischemia during mouse brain development using hyperpolarized 13C

Yiran Chen, Byongsop Lee, Alkisti Mikrogeorgiou, Robert Bok, Ilwoo Park, Subramaniam Sukumar, R Ann Sheldon, A James Barkovich, Donna M Ferriero, Duan Xu
 2:10-2:20 pm  Convolutional Neural Networks For Knee Multi-Tissue Automatic Morphometry And Relaxometry

Berk Norman, Dr. Valentina Pedoia, Dr. Sharmila Majumdar
 2:20-2:30 pm  The Effects of Radiotherapy-Induced Vascular Injury on Cognitive Function in Children treated for Pediatric Brain Tumors

Melanie Morrison, Angela Jakary, Erin Felton, Sabine Mueller, Janine Lupo
 2:30-3:00 pm  Coffee Break
 3:00-4:20 pm  Oral Presentations (Session II)
Moderators: K. Plallv Kolli, MD, and Peder Larson, PhD
 3:00-3:10 pm  Weakly supervised deep feature learning to predict amyloidosis from structural MR brain images

Cyrus Manuel; Duygu Tosun-Turgut
 3:10-3:20 pm  Positron emission tomography imaging of human tumor necrosis factor alpha using zirconium-89 certoluzimab pegol.

Denis R. Beckford-Vera, Alba Gonzalez-Junca, Catherine Fu, Tony L. Huynh, Jessica S Janneck, Niecholle Roco, Joseph E. Blecha, Xiaojuan Li, Mary H Barcellos-Hoff, Benjamin L. Franc, and Henry F. VanBrocklin
 3:20-3:30 pm  Deep Learning For Identification and Quantification of Acute Intraparenchymal Hemorrhage on Head CT

Peter Chang MD; Daniel Chow MD; Leo Sugrue MD
 3:30-3:40 pm  Association between dedicated breast PET and MR imaging features in primary invasive breast cancers

Ella F. Jones, Mimi Poon, Wen Li, Kimberly M. Ray, Youngho Seo, Benjamin L. Franc, Laura J. Esserman, Miguel H. Pampaloni, Bonnie N. Joe and Nola M. Hylton
 3:40-3:50 pm  Auditory and Somatosensory Response in ASD: Evidence for Domain Specificity and Associations with Language

Carly Demopoulos, Ph.D., Nina Yu, B.A., Jennifer Tripp, M.A., Anne N. Brandes-Aitken, B.S., Shivani S. Desai, B.S., Susanna S. Hill, M.D., Ashley D. Antovich, B.S., Julia Harris, OTR/L, Susanne Honma, R.T., Danielle Mizuiri, B.S., Nayara Graciella Mota Miranda, Ph.D., Srikantan S. Nagarajan, Ph.D., and Elysa J. Marco, M.D.
 3:50-4:00 pm  Abnormal muscle forces after hip arthroscopy are related to altered cartilage composition in FAI patients

Michael A Samaan, Alan L Zhang, Jan Neumann, Thomas M Link, Sharmila Majumdar, Richard B Souza
 4:00-4:10 pm  Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition

Chin Hong Tan, Chun Chieh Fan, Elizabeth Mormino, Leo Sugrue,, Iris Broce, Christopher Hess, William Dillon, Luke Bonham, Jennifer Yokoyama, Celeste Karch, James Brewer, Gil Rabinovici, Bruce Miller, Gerald Schellenberg, Karolina Kauppi, Howard Feldman, Dominic Holland, Linda McEvoy, Bradley Hyman, Ole Andreassen, Anders Dale, Rahul Desikan
 4:10-4:20 pm  Hyperpolarized [1-13C] pyruvate as a biomarker for treatment monitoring in lymphoma murine models

Brice Tiret, Adam Elkhaled, IlWoo Park, Ming Lu, Rana Anjum, Lisa Drew, Sebastien Degorce, Michele Mayo, Keith Dillman, James Rubenstein, Myriam Chaumeil
 4:35-6:00 pm  Poster Session, Award Presentations, and Catered Reception
Millberry Union
 4:45 pm  Presentation of the Hasegawa Award

 5:45 pm  Podium and Poster Presentation Awards

Closing Comments - Ronald L. Arenson, MD, Professor and Chair, Department of Radiology and Biomedical Imaging

Poster Presentations

 #  Presenting Author  Abstract Title

 1  Jeffrey Pyne Approximating Ischemic Stroke Location and Abnormal Tissue Regions Through Subtracting NCCT and CTA Scans

 2  Alexander Markes Tibiofemoral Kinematics is Associated with Biochemical Meniscal Alterations After ACL Reconstruction

 3  Susanne Mueller Dynamic functional brain imprint of post-traumatic stress disorder (PTSD) subtypes in task-free fMRI

 4  Eugene Milshteyn Simultaneous T1/T2 Mapping of Hyperpolarized 13C Compounds using the bSSFP Sequence

 5  Jay Yu An advanced post-processing algorithm to improve detectability of brain hemorrhages in flat-panel CT images

 6  Yung-Hua Wang Exploiting the Labile Fe(II) Pool to Image Prostate Cancer with PET

 7  Karuna Subramaniam The neurobiology of self-agency during reality monitoring and its relation with self-agency during speech monitoring

 8  Jeremy Gordon Human Hyperpolarized C-13 MRI Using a Novel Echo-Planar Imaging (EPI) Approach

 9  Mariam Aboian Precision imaging of metastatic and primary brain tumors after radiation with 18F-FDOPA PET-MRI is feasible and cost effective

 10  Solomon Joseph Design and Validation of an iOS App in Tracking Performance during the 30-second Chair Stand Test and Stair Climb Test

 11  David Korenchan Pulse Sequences for Preclinical In vivo pH Imaging with Hyperpolarized [13C]bicarbonate

 12  Jessie Lee Compact Ultrasound Applicator for Hyperthermia Treatment of the TRAMP Model with MR Thermometry in a 14T MRI Scanner

 13  Hecong Qin Imaging in vivo brain glutathione content with hyperpolarized [1-13C] dehydroascorbic acid

 14  ana paula santos lima The impact of Scoring Coronary Artery Calcifications on Lung Cancer Screening CT on distinct populations.

 15  Brian Chung Novel Techniques for MR Metabolic Imaging using Hyperpolarized [2-13C]Pyruvate

 16  Junnian Wei Targeting TSC1 Driven Bladder Cancers with Antibodies to Upregulated and Functionally Important Cell-Surface Proteins

 17  Matt Barkovich Quantitative morphometric evaluation of subcortical regions in neurofibromatosis type 1

 18  Anna Vardapetyan Using Machine Learning to Predict ChemoFilter Parameters for Clearance of Doxorubicin From Physiologic solutions

 19  Eugene Ozhinsky MR Thermometry-guided Ultrasound Hyperthermia of User-Defined Regions

 20  Bennett Ng Rapid 4C Body Composition using Dual-Energy X-Ray Absorptiometry and Bioelectrical Impedance Analysis

 21  Justin Yuan Grey matter volume changes in adolescents participating in a meditation training

 22  Lisa Wilmes Correction of geometric image distortion and gradient nonlinearity: Effects on DTI of breast cancer

 23  Caroline Jordan Aerosol-deposited wireless resonant markers for interventional MRI

 24  Ayushi Gautam Clearance of Cisplatin from Physiologic Solutions with DNA-based ChemoFilter

 25  Natalie Korn Distinguishing Inflammation in the Peripheral Zone of the Prostate by Multiparametric MRI

 26  Hardik Kothare Oral cavity numbing reduces sensorimotor adaptation to altered auditory feedback

 27  Kamalini Ranasinghe Distinct spatiotemporal patterns of resting state neuronal synchrony in Alzheimer’s disease spectrum

 28  Megan Thompson Speech production without the vocal tract

 29  Chloe Najac Acetate metabolism towards fatty acids is down-regulated in IDH1 mutant glioma as shown by 13C MRS

 30  Benjamin Hinton Quantification of Mammographic Masking in Digital Mammography to Predict Interval Cancer Risk

 31  Daniele Mammoli In Vivo Metabolism of Hyperpolarized Pyruvate in Human Brain Tumor Patients

 32  Robert Bok Hyperpolarized 13C-MRI Detects Early Tumor Response Following Knockout of the LDHA Gene in Prostate Cancer

 33  Olga Tymofiyeva Application of machine learning to structural connectome to predict improvement in depressed adolescents with CBT

 34  Ryan Michael Nillo A Longitudinal Analysis of Regional Brain Changes in Anti-NMDAR Encephalitis

 35  Andrew Leynes Direct PseudoCT Generation for Pelvis PET/MRI Attenuation Correction using Deep Convolutional Neural Networks

 36  Nina Sardesh Treatment induced plasticity of motor and language networks in patients with brain lesions

 37  Markus Sommer Picturing Individualized 3D Body Shape Change from Fat Loss and Muscle Gain: The Shape Up! Study

 38  Po-hung Wu Automated cortical bone vessel identification on contrast-enhanced MRI images

 39  Ana Cruz MRI and HR-pQCT Changes Correlate with Michigan Hand Outcome Questionnaire in Rheumatoid Arthritis

 40  Colin Yee Improved design and validation methods of a chemofiltration device in vivo

 41  Thomas Hayes Synthesis and evaluation of C-11 and F-18 VX and Sarin surrogates to assess therapeutic countermeasures

 42  Jinny Sun Characterizing altered glucose and glutamine metabolism of castration-resistant prostate cancer using high resolution NMR

 43  Georgios Batsios PI3K/mTOR inhibition leads to reduction in 2HG production and cell proliferation in IDH1 mutant cells

 44  Marina Radoul Hyperpolarized 13C MRSI monitoring of response to HDAC inhibition in glioblastoma.

 45  Celine Taglang Efficient Method for Deuteration of 13C Labeled Substrates for T1 Prolongation in Hyperpolarized 13C MRI Spectroscopy

 46  Ezinna Nnabue Analysis of Associations between Cartilage Morphology and Biochemistry after ACL Injury and Reconstruction

 47  Alba Gonzalez Junca Functional imaging platform to monitor progression and response to therapy in a pre-clinical model of BCBM

 48  Renuka Sriram Metabolic imaging of rodent placenta using hyperpolarized 13C pyruvate MRI

 49  chang cai Hierarchical Multiscale Bayesian algorithms for robust MEG/EEG source reconstruction

 50  Sarina Bhandari Suicidality in Depressed Adolescents: A Study of Neural Changes with a Mind-Body Intervention

 51  Yi Li Selective Regional TSC1 Gene Expression in Tuberous Sclerosis Complex

 52  Trevor Flynn Functional connectivity underlying attentional deficits in children born preterm

 53  Pavithra Viswanath IDH1 mutation down-regulates choline and ethanolamine metabolism in gliomas

 54  Yan Wang Synthetic Images from Cardiac T1 mapping and Automatic Segmentation for Myocardial Fibrosis Assessment

 55  Jeremy Bancroft Brown Microscale DWI of individual fresh prostate biopsies at 14 T

 56  Leighton Hinkley Multimodal imaging of chronic tinnitus

 57  Sinan Wang Detection of aggressive prostate cancer using new hyperpolarized 13C magnetic resonance imaging probes targeting zinc metabolism

 58  xucheng zhu Slice-selective double spin echo sequence for dynamic C-13 imaging

 59  Donna Murray Brain Metabolite Levels, Especially Glutamate, Affect Functional Connectivity in Alcohol Dependence

 60  Caroline Guglielmetti In vivo metabolic imaging of traumatic brain injury

 61  Inez Raharjo Altered speech production in response to transient mid-utterance formant perturbation